What is the product of the decarboxylation of trytophan?

1 Answer
Dec 7, 2015

The product of decarboxylation of tryptophan is tryptamine.

The structure of tryptophan is

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If you decarboxylate tryptophan, you get tryptamine.

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In the lab, the decarboxylation takes place readily in a high-boiling solvent like cyclohexanol (b.p. 161 °C) containing cyclohex-2-en-1-one as a catalyst.

In cells, the enzyme tryptophan decarboxylase converts tryptophan to tryptamine.