What is the diference between the most common two-dimensional NMR techniques: COSY and HETCOR?
1 Answer
In COSY, the proton spectra are plotted along each axis, while in HETCOR the proton spectrum is on one axis and the
Explanation:
COSY —
(you may also see it written as H,H-COSY)
In COSY, both axes correspond to
The off-diagonal peaks show which protons are coupled to each other.
The COSY spectrum of ethyl but-2-enoate
(from www.chem.ucalgary.ca)
is
(from www.chem.ucalgary.ca)
For example, peak A indicates a coupling between the
This shows that the
HETCOR —
in HETCOR spectra, a proton NMR spectrum is plotted on one axis and the
The peaks show which
Here is the HETCOR spectrum of ethyl but-2-enoate.
(from www.chem.ucalgary.ca)
For example, Peak A indicates that the
This corresponds to the
