Why is 2,4 pentanedione more highly enolized than 1,3 cyclohexanedione?
1 Answer
Jun 19, 2016
Enolization of acetylacetone allows a 6-membered ring, stabilized by hydrogen bonding.
Explanation:
On the other hand, when the cyclic dione enolizes, because the oxygen centres are constrained by the ring, and hydrogen bonding would occur intermolecularly, rather than intramolecularly.
I am trying to think how you would be able to test this hypothesis. Maybe the