How does the reactivity of a nucleophile change across a row in the periodic table?

1 Answer
Jan 3, 2015

The reactivity of a nucleophile decreases from left to right in a row across the Periodic Table.

A nucleophile is a Lewis base that donates an electron pair to an atom other than hydrogen. In organic chemistry, this usually means a carbon atom.

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Electronegativity increases from left to right across the Periodic Table.

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This means that atoms on the right hand side are less likely to donate their electrons to form bonds with other atoms.

Their nucleophilicity decreases from left to right.

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