How do grignard reagents react with water?
1 Answer
Jun 24, 2016
Irreversibly. This is sometimes exploited by chemists.
Explanation:
The carbanionic nucleophile reacts with the electrophilic proton on the water molecule:
The reaction is irreversible, but it does have some synthetic utility if you want to label an hydorcarbyl chain with an isotope of hydrogen,
