Question #c84fc

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Question #c84fc

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Answer 1 · 2017-02-08T16:39:36

It is probably a matter of cost of the acetyl halide.

Explanation:

All three compounds readily react with amines per the equation

${RNH}_{2} + {CH}_{3} CO-X \to {RNH-COCH}_{3} + HX$ $"RNH"_2 + "CH"_3"CO-X" → "RNH-COCH"_3 + "HX"$

The prices of the halides in US dollars are approximately

${CH}_{3} COCl m $100/L$ $"CH"_3"COCl"color(white)(m)"$100/L"$
${CH}_{3} COBr m $300/L$ $"CH"_3"COBr"color(white)(m)"$300/L"$
${CH}_{3} COF m l l $700/L$ $"CH"_3"COF"color(white)(mll)"$700/L"$

Chemists like to choose the cheapest reactant that will do the job.

Hence, acetyl chloride is the reagent of choice.

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