Why is X inactivation important?
1 Answer
Sep 9, 2016
The inactivated X chromosome condenses into a compact structure called as the Barr body. The transcriptionally silent Barr bodies maintain gene equality between males and females.
Explanation:
Unlike the gene poor Y chromosome, the X chromosome contains over 1000 genes, that are essential for proper development and cell viability.
Females carry two copies of X chromosome, resulting in a double dose of X linked genes.
To correct this imbalance, the mammalian females have evolved the unique mechanism of X chromosome inactivation.
