Please,explain me what is lock and key theory of enzyme?

1 Answer
Dec 2, 2017

This model supports that a specific substrate(key) can be inserted into a particular enzyme(lock). Means that enzyme are subtrate-specific.

Explanation:

Lock and Key Model:

Emil Fischer proposed this model in #1894# . According to this model:

  • As one specific key can open only a specific lock, just like that a specific enzyme can convert only one particular substrate into product(s).
  • This model supports that an active site is a rigid structure.
  • And active site play a role of template only. So, there is no modification in the active site before, during or after the reaction.
    http://faculty.ccbcmd.edu/~gkaiser/biotutorials/proteins/fg7.html

#Side# #"Information":#
This model was further improved by Koshland and he named the new model as "Induced fit model" which was practically more accepted.

Hope it helps...