In IgG, what is the antigen binding site formed by?

1 Answer
Jonathan · Stefan V.
Feb 28, 2018

Great question but hard to answer. The correct response is the genetic sequence for the VDJ recombination site for the specific B cell.

Explanation:

Each B cell that makes a single and specific antibody (IgG, IgE - etc.) has to be told what the protein will look like to create the greatest affinity to that antigen. DNA #-># RNA #-># Protein - so, if that one B cell needs to make a specific antibody it has to have the unique gene to do so.

Does this help?

Related questions
See all questions in Immune Responses
Impact of this question
2321 views around the world
You can reuse this answer
Creative Commons License