If a homozygous dominant genotype is 46% what is the dominant allele frequency?

1 Answer
Mar 25, 2017

Well, let's check.

Explanation:

Assuming Hardy-Weinberg conditions are met, we will use the "Hardy-Weinberg equation" which is:

p^2+2pq+q^2=1

Where:
p^2 = "frequency of homozygous dominant genotype"
2pq = "frequency of heterozygous genotype"
q^2 = "frequency of homozygous recessive genotype"

If a homozygous dominant genotype is 46%, that means p^2 = 0.46

Using p+q = 1 where:

p = "frequency of dominant allele"
q = "frequency of recessive allele"

we will find the frequency of the dominant allele, meaning we will solve for p.

If we have p^2 and we need to find p, then using basic algebra:

p^2 = 0.46
sqrt(p^2) = sqrt0.46
p = 0.68

the dominant allele frequency turns out to be 0.68 or 68%