How many grams to toothpaste to kill a rat? One of the leading toothpaste brands advertises Fluoride (NaF) at 1400ppm. And the MSDS for Sodium Fluoride says that 52mg/kg is enough to kill a rat. How would I calculate this?

1 Answer
Feb 20, 2015

You would need 37.1 g of toothpaste to get the job done.

So, let's start with what 1400 ppm actually means. PPM, or parts per million, is used to express really small concentrations of a substance in a solution or a mixture. Mathematically, a 1-ppm concentration has

1 ppm=1 mg1 kg

Every 1 kg of solution contains 1 mg, or 103 grams, of your substance of interest. In this case, the concentration of NaF is 1400 ppm, which means that 1 kg of toothpaste contains 1400 mg of NaF.

All you have to do now is set up a simple conversion factor to see how much toothpaste contains 52 mg of NaF

52 mg NaF1 kg toothpaste1400 mg NaF=0.0371 kg toothpaste

0.0371 kg of toothpaste contain 52 mg of NaF. Expressed in grams, this amount is equal to

0.0371 kg1000 g1 kg=37.1 g